High-affinity bispecific antibody manufacturing Learn how our multi-format screening approach led to high-affinity antibodies. Schneider-Mergener,J. (1998) Elucidation of the interaction of an anti-TGFalpha antibody with its peptide epitope utilizing combinatorial cyclic peptide libraries, binding research, NMR, computer modelling and versatile docking techniques. Bonhaus,D.W. (1997) Bar-code technology and a centralized database: Key components in a radioligand binding program. 1997) Convergent parallel synthesis. 1997) Automated stable-part natural synthesis in micro-plate wells. 1997) Evaluation of various stable-section traps for automated collection and clean-up in the analysis of a number of pesticides in fruits and vegetables after supercritical fluid extraction. 8343 304. Parker, T. D. III., Wright, D. S., and Rossi, D. T. Design and evaluation of an automated stable-part extraction technique-development system to be used with biological fluids. 9855 300. Nihira, S., Kotaki, H., and Nakano, A. High throughput screening by the usage of robotics and high efficiency information dealing with system. 1997) New methods in combinatorial chemistry: Robotics and parallel synthesis.
8303 183. Babiak, J. Transforming your robotics into an infrastructure for the long run. 9636 296. Neary, C. The present and future of automation in drug discovery. 11421 285. McClurg, J. E. Future directions of outsourced bioanalytical companies: The Bioanalytical business. 9311 233. Getek, T., Mei, W., and Hariharan, S. Enhancing productiveness for bioanalytical assays: Utilization of automated SPE isolation and LC/MS/MS for steroid evaluation. 8879 297. Neil, W., Weller, H. N., Lawrence, R. M., and Young, M. G. Adaptation of liquid handlers to the automation of combinatorial organic chemistry. 8786 208. Charbonneau, R., Long, W., Hennessey, J., and Rubinstein, L. Using the Biomek 2000 to automate an EIA for the quantitation of polysaccharides. 8341 212. Cook, J. S., Hynd, B., Kozikowski, B., McOsker, C. C., Paugh, D., Rasmusen, Okay., Sway, J., and Whitten, J. Establishing a excessive throughput screening facility. 8293 235. Goodman, B. A., Bjergarde, K., and Boymel, J. L. Developing a high speed synthesis paradigm the work station approach. The workstation approach. In: Anonymous. 8333 225. Feiglin, M. N. and Russell, B. J. A “element” based strategy to laboratory automation. 12254 255. Kealy,M. (1997) Automation of 96-nicely strong phase extraction procedures with the Packard MultiPROBE.
9741 261. Kolb,A.J. (1997) Automation and robotics: Introduction. 1997) Photolabile linker for the stable-section synthesis of base-delicate oligonucleotides. 1997) Matrix-assisted laser desorption ionization time-of-flight mass spectrometry as a rapid high quality management methodology in oligonucleotide synthesis. 1997) Carbamate linkers as latent N-methylamines in solid part synthesis. 1997) Incorporation of 5′-N-Boc-2′,5′-dideoxynucleoside-3′-O-phosphoramidites into oligonucleotides by automated synthesis. 1997) Automated synthesis of double dye-labeled oligonucleotides utilizing tetramethylrhodamine (TAMRA) strong supports. 1998) Optimized automated solid phase synthesis of oligonucleotides and derivatives. 1998) Rapid optimization of an ICE inhibitor synthesis utilizing multiple response circumstances in a parallel array. 1997) Rapid discovery and optimization of biologically energetic small molecules using automated synthesis methods. 1997) Automated online strong-part extraction-fuel chromatography with nitrogen-phosphorus detection: Willpower of benzodiazepines in human plasma. 1987) Laboratory Robotics: A Guide to Planning, Programming, and Applications. 8294 205. Cargill, J. The usage of reactive fragment structure transformations for automated structure technology in automated combinatorial chemistry with applications to diversity analysis. 14384 162. Radl,S. (1998) Use of combinatorial chemistry to hurry drug discovery.
1998) I.F.C.U.Beckman Instruments. Oxidizing reagent to be used in oligonucleotide synthesis. 1995) E.C.U.Chiron Corporation. Assay system with captured particle reagent. 1998) E.C.U.Chiron Corporation. Synthesis of N-substituted oligomers. Zuckermann,R.N. (1998) Submonomer approaches for the generation of molecular variety: Nonnatural oligomer and organic template libraries. 9578 214. Cunningham, J. D. and Kelly, D. A. Coping with company rightsizing using the 4 R’s. 1997) Synthesis of tertiary amines using a polystyrene (REM) resin. 1997) Automated preparation of branched oligodeoxyribonucleotide analogs using arabino-uridine as branching nucleotide. 11761 273. Lindsey,J.S. (1997) Automated approaches to reaction optimization. 8268 271. Lenz, S., Marples, E., Garcia, M., and Reichman, M. High throughput robotic system for performing stablely transfected cell primarily based screening assays. 9332 187. Banks, M., Fogarty, S., Valler, M., Mills, K., O’Brien, S., Binnie, A., and Houston, J. Automated high throughput screening to help the drug hunter at Glaxo Wellcome. 8889 243. Heide, M., Madsen, J., and Jensen, N. B. A robotic system for agar diffusion testing. 8320 258. Kibbey,C.E. (1997) An automated system for the purification of combinatorial libraries by preparative LC/MS. 1997) L.J.Suntory. Chinese scorpion (Buthus martensi) toxin-associated peptides. 9004 194. Biddlecombe, R. A. and Pleasance, S. Microlute(TM) a semi-automated stable section extraction system in the 96 well format.